N-Acetyl-L-tyrosine ethyl ester (ATEe) hydrolytic activities of diseased human palatine tonsils. Possible pathogenesis of recurrent acute tonsillitis.

Abstract	The N-acetyl-L-tyrosine ethyl ester (ATEe)-hydrolysing activities of tonsillar extracts in cases of recurrent acute tonsillitis decreased more than those in less severe cases of chronic tonsillitis and in cases of obstructive enlargement of the palatine tonsil. Since ATEe is hydrolysed by C1-esterase, the ATEe hydrolytic activity of the tonsil might be related to the C1-activating system of the tonsil. This indicates that tonsils in which ATEe hydrolytic activities are low, repeatedly and severely, become infected, possibly due to easy invasion of micro-organisms.
Authors	H Ogawa, Y Yamazaki, A Takada, Y Takada
Journal	Acta oto-laryngologica. Supplementum (Acta Otolaryngol Suppl) Vol. 416 Pg. 56-62 ( 1984) ISSN: 0365-5237 [Print] Norway
PMID	6335943 (Publication Type: Journal Article)
Chemical References	Tyrosine ethyl N-alpha-acetyl-tyrosinate Complement C1s
Topics	Acute Disease Adolescent Adult Biopsy Child Child, Preschool Complement C1s (metabolism) Humans Hydrolysis Hypertrophy Middle Aged Palatine Tonsil (enzymology, metabolism, pathology) Recurrence Tonsillitis (enzymology, etiology) Tyrosine (analogs & derivatives, metabolism)

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