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T cell nature of adjuvant peptide--induced antitumor cell-mediated cytotoxicity.

Abstract
The direct cell-mediated antitumor cytotoxicity induced by coupling a murine methylcholanthrene-induced sarcoma with N-acetylmuramyl-L-alanyl-D-isoglutamine (adjuvant peptide) was eliminated by treatment of effector cells with anti-Thy 1.2 or anti-Lyt 2.2 monoclonal antibody and complement. Cytotoxicity was not H-2 restricted.
AuthorsA E Eggers, L Tarmin
JournalJournal of biological response modifiers (J Biol Response Mod) Vol. 3 Issue 4 Pg. 387-90 (Aug 1984) ISSN: 0732-6580 [Print] United States
PMID6332881 (Publication Type: Journal Article, Research Support, U.S. Gov't, P.H.S.)
Chemical References
  • H-2 Antigens
  • Acetylmuramyl-Alanyl-Isoglutamine
Topics
  • Acetylmuramyl-Alanyl-Isoglutamine (immunology)
  • Animals
  • Cytotoxicity, Immunologic
  • H-2 Antigens (immunology)
  • Immunity, Cellular
  • Mice
  • Mice, Inbred Strains
  • T-Lymphocytes (immunology)

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