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Collagen stimulating factors from lung in experimental paraquat poisoning demonstrated in vitro and in vivo.

Abstract
Collagen stimulating factors, previously described in experimental liver injury and healing skin wounds, have now been found in experimental paraquat lung injury. These factors are active not only in culture but also in vivo. The evidence from this third example of tissue injury points to an important pathological role in chronic inflammation.
AuthorsW D Thompson, R S Patrick
JournalJournal of clinical pathology (J Clin Pathol) Vol. 37 Issue 5 Pg. 537-41 (May 1984) ISSN: 0021-9746 [Print] England
PMID6327775 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Tissue Extracts
  • Collagen
  • Procollagen-Proline Dioxygenase
  • Paraquat
Topics
  • Animals
  • Collagen (biosynthesis)
  • Fibroblasts (enzymology)
  • Liver (enzymology, metabolism)
  • Lung (metabolism)
  • Male
  • Mice
  • Paraquat (poisoning)
  • Procollagen-Proline Dioxygenase (metabolism)
  • Rats
  • Rats, Inbred Strains
  • Tissue Extracts (pharmacology)

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