[Effect of trihydroxyoctadecadiene acids from Bryonia alba L. on the activity of glycogen metabolism enzymes in alloxan diabetes].

Abstract

It was shown previously in experiments on white rats with alloxan diabetes that trihydroxyoctadecadiene acids from Bryonia alba L. have a hypoglycemic action. The present paper is concerned with the effects of the above-indicated compounds on the activity of glycogen phosphorylase (a- and b-forms), phosphoprotein phosphatase and hexokinase in liver and muscle tissues of white rats with alloxan diabetes. One of the possible mechanisms of the hypoglycemic action of trihydroxyoctadecadiene acids is discussed.

• Authors: G S Vartanian, G K Parsadanian, K G Karagezian
• Journal: Biulleten' eksperimental'noi biologii i meditsiny (Biull Eksp Biol Med) Vol. 97 Issue 3 Pg. 295-7 (Mar 1984) ISSN: 0365-9615 [Print] Russia (Federation)
• Vernacular Title: Vliianie trioksioktadekadienovykh kislot iz Bryonia alba L. na aktivnost' fermentov obmena glikogena pri alloksanovom diabete.
• PMID: 6322880 (Publication Type: English Abstract, Journal Article)

Chemical References

• Fatty Acids, Unsaturated
• Fatty Alcohols
• Hypoglycemic Agents
• Phosphorylase a
• Phosphorylase b
• Hexokinase
• Phosphoprotein Phosphatases

Topics

• Animals
• Diabetes Mellitus, Experimental (enzymology)
• Fatty Acids, Unsaturated (pharmacology)
• Fatty Alcohols (pharmacology)
• Hexokinase (metabolism)
• Hypoglycemic Agents (pharmacology)
• Liver (drug effects, enzymology)
• Muscles (drug effects, enzymology)
• Phosphoprotein Phosphatases (metabolism)
• Phosphorylase a (metabolism)
• Phosphorylase b (metabolism)
• Rats