[Oral acyclovir therapy of virologically proven intraocular herpes simplex virus infections].

Abstract

Three patients with severe intraocular herpetic disease (focal serous iritis, endotheliitis, trabeculitis) were treated with oral acyclovir. Inflammatory signs subsided promptly although only low-dose steroid eye drops were administered in addition to antiviral therapy. Normally, the viral etiology of suspected intraocular herpetic disease remains equivocal because virologic proof is lacking. In these three cases, however, herpes simplex virus was isolated from the aqueous humor before initiation of therapy, and the viral nature of the diseases treated could thus be proven.

• Authors: R Sundmacher
• Journal: Klinische Monatsblatter fur Augenheilkunde (Klin Monbl Augenheilkd) Vol. 183 Issue 4 Pg. 246-50 (Oct 1983) ISSN: 0023-2165 [Print] Germany
• Vernacular Title: Orale Acyclovir-Therapie virologisch nachgewiesener intraokularer Herpes simplex Virus Infektionen.
• PMID: 6316022 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Acyclovir

Topics

• Acyclovir (therapeutic use)
• Administration, Oral
• Adult
• Aqueous Humor (microbiology)
• Female
• Humans
• Keratitis, Dendritic (drug therapy, microbiology)
• Male
• Middle Aged
• Simplexvirus (isolation & purification)