A pharmacokinetic study of pentachlorophenol poisoning and the effect of forced diuresis.

Abstract

A pharmacokinetic study of an intentional pentachlorophenol ingestion by an elderly human has been undertaken. Information on the presence or absence of forced diuresis either continuously or for a short restricted period indicates that such treatment would materially reduce the body burden of pentachlorophenol. It is suggested that forced diuresis is the treatment of preference for such intoxication at this time.

• Authors: J F Young, T J Haley
• Journal: Clinical toxicology (Clin Toxicol) Vol. 12 Issue 1 Pg. 41-8 ( 1978) ISSN: 0009-9309 [Print] United States
• PMID: 630820 (Publication Type: Journal Article)

Chemical References

• Chlorophenols
• Diuretics
• Mannitol
• Furosemide
• Pentachlorophenol

Topics

• Chlorophenols (poisoning)
• Computers, Analog
• Computers, Hybrid
• Diuretics (therapeutic use)
• Furosemide (therapeutic use)
• Humans
• Kinetics
• Mannitol (therapeutic use)
• Models, Biological
• Pentachlorophenol (metabolism, poisoning)