Low nickel diet in the treatment of patients with chronic nickel dermatitis.

Abstract

Of 28 patients with chronic nickel dermatitis 17 experienced aggravation following oral ingestion of 2.5 mg nickel, but not a placebo tablet. The dermatitis of 9 of the 17 patients improved during a period of 6 weeks on a low nickel diet. The dermatitis of 7 of the 9 patients flared again when a normal diet was resumed. Nickel excretion over a 24-h period was measured for 14 of the 17 patients by atomic absorption spectrophotometry before, during, and after the diet. Reduced excretion was seen during the diet with no statistically significant difference between patients whose dermatitis improved during the diet and those whose dermatitis showed no change.

• Authors: K Kaaber, N K Veien, J C Tjell
• Journal: The British journal of dermatology (Br J Dermatol) Vol. 98 Issue 2 Pg. 197-201 (Feb 1978) ISSN: 0007-0963 [Print] England
• PMID: 629873 (Publication Type: Journal Article)

Chemical References

• Nickel

Topics

• Chronic Disease
• Dermatitis, Contact (diet therapy, etiology, urine)
• Female
• Humans
• Male
• Nickel (administration & dosage, adverse effects, urine)