[Anticonvulsant action of pargyropyranone in various models of experimental epilepsy in the cat].

Abstract

The new anticonvulsant drug pargypiranone was studied in different models of experimental epilepsy in cat (penicillin and Premarin cortical focus, cobalt cortical focus, penicillin generalized epilepsy). The drug proved to possess a strong anticonvulsant effect upon focal electroclinical phenomena and a poor effect on penicillin generalized epilepsy. It seems probably that pargypyranone has a valid effect on partial epileptic seizures.

• Authors: R Mutani, L Durelli, S Piredda, G P Sechi, S Traccis
• Journal: Rivista di patologia nervosa e mentale (Riv Patol Nerv Ment) 1982 Sep-Oct Vol. 102 Issue 5 Pg. 193-200 ISSN: 0035-6433 [Print] Italy
• Vernacular Title: Azione anticomiziale del pargypyranone in diversi modelli di epilessia sperimentale nel gatto.
• PMID: 6296988 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Anticonvulsants
• Coumarins
• Estrogens, Conjugated (USP)
• Cobalt
• pargyropyranone
• Penicillin G

Topics

• Animals
• Anticonvulsants
• Cats
• Cerebral Cortex (drug effects)
• Cobalt
• Coumarins (therapeutic use)
• Estrogens, Conjugated (USP)
• Penicillin G
• Seizures (chemically induced, drug therapy)