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Intervention with epinephrine in hypotension associated with mastocytosis.

Abstract
The occurrence of the episodes of vasodilatory hypotension can be a life-threatening manifestation of systemic mastocytosis. This article describes the reversal by epinephrine of episodes of severe hypotension in two hospitalized patients with mastocytosis. Recognition of the efficacy of epinephrine in hypotension associated with mastocytosis can be important when other methods fail to restore hemodynamic stability.
AuthorsJ Turk, J A Oates, L J Roberts 2nd
JournalThe Journal of allergy and clinical immunology (J Allergy Clin Immunol) Vol. 71 Issue 2 Pg. 189-92 (Feb 1983) ISSN: 0091-6749 [Print] United States
PMID6296213 (Publication Type: Case Reports, Journal Article, Research Support, U.S. Gov't, P.H.S.)
Chemical References
  • Prostaglandins D
  • 9-hydroxy-11,15-dioxo-2,3,18,19-tetranorprost-5-ene-1,20-dioic acid
  • Histamine
  • Creatinine
  • Cyclic AMP
  • Epinephrine
Topics
  • Aged
  • Animals
  • Creatinine (urine)
  • Cyclic AMP (physiology)
  • Dogs
  • Epinephrine (therapeutic use)
  • Female
  • Guinea Pigs
  • Histamine (urine)
  • Humans
  • Hypotension (drug therapy, etiology)
  • Male
  • Mast Cells (physiology)
  • Prostaglandins D (urine)
  • Rats
  • Urticaria Pigmentosa (complications)

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