[Simultaneous occurrence of pituitary adenoma and thyrogenic hyperthyroidism].

Abstract

Subtotal tumour removal had been performed in a 34-year-old female patient for an extensive intra- and suprasellar expansive process. The considerably increased prolactin level did not decrease postoperatively, but normalised only after a three months bromocriptine treatment. The primary hyperthyroidism has been recovering after administering methimazolum. In a second case was reported on a 65-year-old female patient, suffering from rachitic dwarfism, stenosis of the aortic valve and tumour of the hypophysis, causing acromegaly, whose diabetes mellitus of contrainsular type could have been hardly balanced with insulin of a 128-unit-dose daily, and whose hyperthyroidism was due to an autonomous adenoma of the thyroid gland, first I-131 treatment was administered and she got into an euthyroid state. Six weeks following the removal of the acidophilic adenoma of the hypophysis administration of insulin could have been ceased, and the results of her growth hormone became normal. The clinical picture partly corresponds with Troell-Junet's syndrome.

• Authors: M Góth, I Szabolcs, G Irsy, G Szilágyi, D Afra, E Pásztor
• Journal: Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete (Z Gesamte Inn Med) Vol. 37 Issue 6 Pg. 183-6 (Mar 15 1982) ISSN: 0044-2542 [Print] Germany
• Vernacular Title: Gleichzeitiges Auftreten eines Adenoms der Hypophyse und einer thyreogenen Hyperthyreose.
• PMID: 6283751 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Methimazole

Topics

• Acromegaly (etiology)
• Adenoma (complications)
• Adenoma, Acidophil (complications, surgery)
• Adenoma, Chromophobe (complications, surgery)
• Adult
• Aged
• Diabetes Complications
• Female
• Humans
• Hyperthyroidism (complications, drug therapy, etiology)
• Methimazole (therapeutic use)
• Pituitary Neoplasms (complications, surgery)
• Thyroid Neoplasms (complications, drug therapy)