Calcium pyrophosphate dihydrate deposition disease and familial hypomagnesemia.

Abstract

A 40-year-old woman presented with calcium pyrophosphate synovitis and chondrocalcinosis. She was subsequently found to have hypomagnesemia, as did her 22-year-old son. Metabolic studies demonstrated normal gastrointestinal absorption of magnesium, and impaired renal conservation of magnesium without other evidence of renal tubular dysfunction. It seems likely that a genetically determined abnormality of magnesium metabolism was responsible for the occurrence of chondrocalcinosis in this patient.

• Authors: S C Milazzo, M J Ahern, L G Cleland, D R Henderson
• Journal: The Journal of rheumatology (J Rheumatol) 1981 Sep-Oct Vol. 8 Issue 5 Pg. 767-71 ISSN: 0315-162X [Print] Canada
• PMID: 6273553 (Publication Type: Case Reports, Journal Article)

Chemical References

• Diphosphates
• Magnesium
• Calcium
• Calcium Pyrophosphate

Topics

• Adult
• Calcium (metabolism)
• Calcium Pyrophosphate (physiology)
• Chondrocalcinosis (complications)
• Crystallization
• Digestive System (metabolism)
• Diphosphates (physiology)
• Female
• Humans
• Magnesium (metabolism)
• Magnesium Deficiency (complications, genetics, metabolism)
• Synovitis (complications)