A comparative study of floctafenine (Idarac) and ibuprofen in the treatment of osteoarthrosis.

Abstract

A two-by-two-week crossover trial was conducted in patients with osteoarthrosis, using a double-dummy technique of drug administration. The drugs used were floctafenine (Idarac) and ibuprofen both given in a dose of 200 mg four times daily. Both drugs provided comparable relief of pain. Side-effects were few and generally mild. The results indicate that in the treatment of osteoarthrosis, floctafenine is comparable to ibuprofen (in the dose used in the study) in terms of efficacy and toxicity.

• Authors: V M Rhind, P A Leatham, V Wright, F A Akbar, W W Downie
• Journal: The Journal of international medical research (J Int Med Res) Vol. 6 Issue 1 Pg. 11-3 ( 1978) ISSN: 0300-0605 [Print] England
• PMID: 627302 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)

Chemical References

• Quinolines
• Ibuprofen

Topics

• Aged
• Female
• Humans
• Ibuprofen (adverse effects, therapeutic use)
• Male
• Middle Aged
• Osteoarthritis (drug therapy)
• Quinolines (adverse effects, therapeutic use)