Prolactin, hypercalcemia and corpuscles of Stannius in seawater eels.

Abstract

In intact eels in sea water (SW), ovine prolactin (PRL) treatment induces hypercalcemia, but its mechanism of action, which is discussed, remains to be defined. Corpuscles of Stannius (CSt) are modified simultaneously: two cell categories then become evident. The first cell type (type 1) predominates; it has an oval shape and large granules, it shows a nuclear and nucleolar hypertrophy and a mitotic activity, and appears greatly stimulated by PRL; it may elaborate a hypocalcemic factor (hypocalcin) which would compensate for the PRL-induced hypercalcemia. A similar effect, although slightly less intense, is detected in hypophysectomized-PRL treated eels in SW. A second cell type (type 2), is more elongated, smaller in size, and has an oval nucleus and fine granules. Scarcely less active in SW, it is significantly stimulated by PRL despite an increased blood sodium and potassium level. This experiment does not help to clarify its function.

• Authors: M Olivereau, J Olivereau
• Journal: Cell and tissue research (Cell Tissue Res) Vol. 186 Issue 1 Pg. 81-96 (Jan 09 1978) ISSN: 0302-766X [Print] Germany
• PMID: 627014 (Publication Type: Journal Article)

Chemical References

• Prolactin

Topics

• Animals
• Cell Nucleus
• Eels (anatomy & histology, physiology)
• Hypercalcemia (chemically induced)
• Hypertrophy
• Hypophysectomy
• Kidney (cytology)
• Male
• Mitosis
• Prolactin (pharmacology)
• Seawater
• Water-Electrolyte Balance