Pyrophosphate arthritis with local amyloid deposition.

Abstract

Pyrophosphate and capsular chondromatosis were demonstrated histologically in 15 cases, 14 of which also exhibited local deposition of amyloid. A systematic examination of the joint capsule in 57 consecutive hip replacement operations for osteoarthritis revealed these changes in 6 of the cases (10.5 per cent). Microscopic examination which was done if intraarticular calcifications were grossly visible at operation, showed the same changes in 8 knees, 4 with osteoarthritis and 4 with meniscal disease. The changes were also seen in the menisci. Only one patient was suffering from chronic, polyarticular pyrophosphate arthritis. In the other cases neither change had been expected a priori, and the patients had no signs of systemic articular disease or amyloidosis. Most of them were elderly, but in good health.

• Authors: K H Sørensen, P S Teglbjaerg, C Ladefoged, H E Christensen
• Journal: Acta orthopaedica Scandinavica (Acta Orthop Scand) Vol. 52 Issue 2 Pg. 129-33 ( 1981) ISSN: 0001-6470 [Print] England
• PMID: 6264732 (Publication Type: Journal Article)

Chemical References

• Amyloid
• Diphosphates

Topics

• Adult
• Aged
• Amyloid (metabolism)
• Chondrocalcinosis (metabolism, pathology)
• Diphosphates (metabolism)
• Female
• Humans
• Joints (pathology)
• Male
• Middle Aged
• Osteoarthritis (metabolism, pathology)