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Progressive multifocal leukoencephalopathy: immunofluorescent demonstration of simian virus 40 antigen in CSF cells and response to cytarabine therapy.

Abstract
We report an instance of progressive multifocal leukoencephalopathy in which cytarabine administration was successful as demonstrated by clinical course and follow-up computerized tomography studies. In this case, simian virus 40 (SV40) antigen was demonstrated in CSF cells by the indirect immunofluorescence technique.
AuthorsA C Peters, J Versteeg, G T Bots, W Boogerd, G J Vielvoye
JournalArchives of neurology (Arch Neurol) Vol. 37 Issue 8 Pg. 497-501 (Aug 1980) ISSN: 0003-9942 [Print] United States
PMID6251791 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Antigens, Viral
  • Cytarabine
  • Vidarabine
Topics
  • Adult
  • Antigens, Viral (cerebrospinal fluid)
  • Cytarabine (therapeutic use)
  • Fluorescent Antibody Technique
  • Humans
  • Leukoencephalopathy, Progressive Multifocal (drug therapy, immunology)
  • Male
  • Simian virus 40 (immunology)
  • Vidarabine (therapeutic use)

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