Effect on dental caries of a stannous fluoride-calcium pyrophosphate dentrifice in an adult population: one-year results.

Abstract

The first year of a two-year double-blind clinical trial of the anticaries effectiveness of a stannous fluoride-calcium pyrophosphate (SnF2-CPP) dentifrice as compared to a placebo control dentifrice involved 1,337 adult subjects, 18 to 78 years of age. Adult subjects were examined for dental caries at a baseline examination and after one year of ad lib dentifrice usage by an experienced clinical examiner using a visual-tactile examination and a radiographic evaluation. Results of the study after one year indicate a significant (P < 0.05) 33.3% difference in new caries formation with use of the SnF2-CPP dentifrice as compared to the placebo control based on the DMFS score.

• Authors: K H Lu, J D Hanna, J K Peterson
• Journal: Pharmacology and therapeutics in dentistry (Pharmacol Ther Dent) Vol. 5 Issue 1-2 Pg. 11-6 ( 1980) ISSN: 0001-4389 [Print] United States
• PMID: 6251487 (Publication Type: Clinical Trial, Comparative Study, Controlled Clinical Trial, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Cariostatic Agents
• Dentifrices
• Diphosphates
• Placebos
• Tin Fluorides
• Fluorides
• Calcium Pyrophosphate

Topics

• Adolescent
• Adult
• Aged
• Calcium Pyrophosphate (therapeutic use)
• Cariostatic Agents
• DMF Index
• Dental Caries (prevention & control)
• Dentifrices (therapeutic use)
• Diphosphates (therapeutic use)
• Fluorides (therapeutic use)
• Humans
• Middle Aged
• Placebos
• Tin Fluorides (therapeutic use)