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Effects of new antimitotic antibiotics, ansamitocins, on the growth of murine tumors in vivo and on the assembly of microtubules in vitro.

AuthorsK Ootsu, Y Kozai, M Takeuchi, S Ikeyama, K Igarashi, K Tsukamoto, Y Sugino, T Tashira, S Tsukagoshi, Y Sakurai
JournalCancer research (Cancer Res) Vol. 40 Issue 5 Pg. 1707-17 (May 1980) ISSN: 0008-5472 [Print] United States
PMID6245801 (Publication Type: Journal Article)
Chemical References
  • Antibiotics, Antineoplastic
  • DNA, Neoplasm
  • Oxazines
  • Tubulin
  • Maytansine
  • Bucladesine
  • ansamitocins
Topics
  • Animals
  • Antibiotics, Antineoplastic (pharmacology)
  • Bucladesine (antagonists & inhibitors)
  • DNA, Neoplasm (biosynthesis)
  • Maytansine (analogs & derivatives, pharmacology)
  • Mice
  • Microtubules (drug effects)
  • Mitosis (drug effects)
  • Neoplasms, Experimental (drug therapy, pathology)
  • Oxazines (pharmacology)
  • Protein Binding (drug effects)
  • Tubulin (metabolism)

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