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Chemotherapy trials in malignant pheochromocytoma: report of two patients and review of the literature.

Abstract
Two patients with metastatic pheochromocytoma received chemotherapy with 5-fluorouracil, cyclophosphamide, and streptozotocin. A biochemical response occurred in one instance. A review of the literature and the results in the reported patients indicate cyclophosphamide and/or streptozotocin may have activity in this neoplasm.
AuthorsR M Bukowski, D G Vidt
JournalJournal of surgical oncology (J Surg Oncol) Vol. 27 Issue 2 Pg. 89-92 (Oct 1984) ISSN: 0022-4790 [Print] United States
PMID6237229 (Publication Type: Case Reports, Clinical Trial, Journal Article)
Chemical References
  • Catecholamines
  • Streptozocin
  • Cyclophosphamide
  • Fluorouracil
Topics
  • Adrenal Gland Neoplasms (drug therapy, metabolism)
  • Adult
  • Catecholamines (metabolism)
  • Clinical Trials as Topic
  • Cyclophosphamide (administration & dosage)
  • Drug Therapy, Combination
  • Fluorouracil (administration & dosage)
  • Humans
  • Male
  • Pheochromocytoma (drug therapy, metabolism)
  • Prospective Studies
  • Streptozocin (administration & dosage)

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