[Chemonucleolysis in the treatment of sciatica caused by herniated disk].

Abstract

Chemonucleolysis is an effective treatment of sciatica due to herniated lumbar disc after conservative treatments have failed. Provided the proper technique is applied and the patients are well selected (complete herniation or herniation within a narrow spinal canal being excluded), surgery can be avoided in the majority of cases. Chemonucleolysis does not in any way complicate subsequent surgery if required and post-nucleolysis surgery gives the same results as first intention surgery. The method, therefore, should not be regarded as an alternative to surgery but as the last stage of conservative treatment. Allergic reactions are the only true side-effects and require special precautions.

• Authors: M Benoist, A Deburge, J Busson
• Journal: Presse medicale (Paris, France : 1983) (Presse Med) Vol. 13 Issue 12 Pg. 733-6 (Mar 24 1984) ISSN: 0755-4982 [Print] France
• Vernacular Title: La chimionucléolyse dans le traitement des sciatiques par hernie discale.
• PMID: 6231579 (Publication Type: Journal Article, Review)

Chemical References

• Endopeptidases
• Chymopapain

Topics

• Anaphylaxis (chemically induced)
• Animals
• Chymopapain (adverse effects, therapeutic use, toxicity)
• Endopeptidases (therapeutic use)
• Humans
• Injections (methods)
• Intervertebral Disc (diagnostic imaging, drug effects)
• Intervertebral Disc Displacement (complications, diagnostic imaging, drug therapy)
• Radiography
• Sciatica (etiology, therapy)