Abstract |
Cortisol and dehydroepiandrosterone sulphate ( DHAS) were measured in saliva from postmenopausal women with primary breast cancer and a control group of comparable age. Specimens were collected at 2-hr intervals during wake-span for two consecutive days, and circadian rhythmicity was demonstrated for each of the hormones in both populations. The marginally elevated levels of cortisol and lower levels of DHAS associated with the cancer group, and the larger inter-subject variation, make it unlikely that these hormone measurements would be of value in identifying women at risk of developing breast cancer.
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Authors | G F Read, D W Wilson, F C Campbell, H W Holliday, R W Blamey, K Griffiths |
Journal | European journal of cancer & clinical oncology
(Eur J Cancer Clin Oncol)
Vol. 19
Issue 4
Pg. 477-83
(Apr 1983)
ISSN: 0277-5379 [Print] England |
PMID | 6222900
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Dehydroepiandrosterone
- Dehydroepiandrosterone Sulfate
- Hydrocortisone
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Topics |
- Aged
- Breast Neoplasms
(metabolism)
- Circadian Rhythm
- Dehydroepiandrosterone
(analogs & derivatives, analysis)
- Dehydroepiandrosterone Sulfate
- Female
- Humans
- Hydrocortisone
(analysis)
- Menopause
- Middle Aged
- Risk
- Saliva
(analysis)
- Statistics as Topic
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