Secondary acrylamides in Nyloprint printing plate as a source of contact dermatitis.

Abstract

Several chemically pure fractions have been isolated from Nyloprint printing plates. 5 of the fractions elicited positive patch test reactions in 7 Nylonprint allergic printers. 4 of the 5 components were analysed by means of nuclear magnetic resonance, infrared spectrophotometry, mass spectrometry and elemental analysis. The fractions were identified as N,N'-methylene-bis-acrylamide. N,N'-[oxybis(methylene)]bis-2-propenamide, N,N'-[1,2-ethanediylbis(oxymethylene)]-2-propenamide, and a new compound N-[(2-hydroxyethoxy)-methyl]-2-propenamide. All of the analysed fractions have the common feature of being secondary acrylamides.

• Authors: N B Pedersen, M A Chevallier, A Senning
• Journal: Contact dermatitis (Contact Dermatitis) Vol. 8 Issue 4 Pg. 256-62 (Jul 1982) ISSN: 0105-1873 [Print] England
• PMID: 6213358 (Publication Type: Journal Article)

Chemical References

• Acrylamides

Topics

• Acrylamides (analysis, chemical synthesis, toxicity)
• Dermatitis, Occupational (etiology)
• Humans
• Magnetic Resonance Spectroscopy
• Male
• Printing
• Skin Tests