Weaver-Smith syndrome. A case study with long-term follow-up.

Abstract

We studied a 6-year-old-boy who was followed up from infancy and who had Weaver-Smith syndrome (WSS), a syndrome characterized by excessive growth, dysmorphic facies, psychomotor retardation, and specific radiologic features. The child's height and bone age were far greater than his chronological age and he demonstrated hypothyroidism at the age of 6 years, but had no endocrinologic abnormalities when he was examined at 11 months of age and again at 4 years of age. We compared the clinical and laboratory features of this child with all other reported cases of WSS.

• Authors: N Amir, E Gross-Kieselstein, H J Hirsch, E Lax, R Silverberg-Shalev
• Journal: American journal of diseases of children (1960) (Am J Dis Child) Vol. 138 Issue 12 Pg. 1113-7 (Dec 1984) ISSN: 0002-922X [Print] United States
• PMID: 6209982 (Publication Type: Case Reports, Comparative Study, Journal Article)

Chemical References

• Blood Glucose
• Pituitary Hormones, Anterior
• Thyroid Hormones

Topics

• Age Determination by Skeleton
• Blood Glucose (analysis)
• Child
• Developmental Disabilities (complications)
• Facial Bones (abnormalities)
• Follow-Up Studies
• Growth Disorders (blood, complications, diagnostic imaging)
• Humans
• Hypothyroidism (blood, complications)
• Male
• Micrognathism (complications)
• Pituitary Hormones, Anterior (blood)
• Skull (abnormalities)
• Syndrome
• Thyroid Hormones (blood)