Apneas and oscillation of cardiac ectopy in Cheyne-Stokes breathing during sleep.

Abstract

Previous investigators have described heart rate oscillations (1,2) and various arrhythmias (3-5) during Cheyne-Stokes breathing. To our knowledge, however, this is the first report describing cardiac ectopic beats oscillating with the identical frequency as ventilatory movement and SaO2 in Cheyne-Stokes breathing during sleep. This case is also the first to document with polygraphic sleep recordings the suggested efficacy of acetazolamide (26) in abolishing the apneas of Cheyne-Stokes breathing during sleep. However, generalizations regarding the impact of ventilation on cardiac ectopy and the therapeutic effect of acetazolamide will require prospective studies on multiple patients with Cheyne-Stokes breathing during sleep.

• Authors: L J Findley, M R Blackburn, A L Goldberger, A J Mandell
• Journal: The American review of respiratory disease (Am Rev Respir Dis) Vol. 130 Issue 5 Pg. 937-9 (Nov 1984) ISSN: 0003-0805 [Print] United States
• PMID: 6208837 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Acetazolamide

Topics

• Acetazolamide (therapeutic use)
• Aged
• Cardiac Complexes, Premature (physiopathology)
• Cheyne-Stokes Respiration (drug therapy, physiopathology)
• Electrocardiography
• Heart Conduction System (physiopathology)
• Heart Rate
• Humans
• Male
• Respiration
• Respiration Disorders (physiopathology)
• Sleep Apnea Syndromes (drug therapy, physiopathology)