Phenotypic characterization of skin-infiltrating cells in pagetoid reticulosis by monoclonal antibodies.

The immunological characterization of the infiltrating cells in a patient with a disseminated form of Pagetoid reticulosis (PR) was carried out-in histological section and cell suspensions--by means of a panel of monoclonal antibodies and classical markers (E-rosette and surface immunoglobulins (SIg]. Most of the infiltrating cells were seen to be mature T-lymphocytes with a suppressor/cytotoxic phenotype (T11+, T3+, T8+, T4-). The results suggest that this variant of PR represents a special histological type of cutaneous T cell lymphoma.
AuthorsM Gonzalez, M Martin-Pascual, J San Miguel, M D Caballero, A López Borrasca
JournalActa dermato-venereologica (Acta Derm Venereol) Vol. 64 Issue 5 Pg. 421-4 ( 1984) ISSN: 0001-5555 [Print] SWEDEN
PMID6208722 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Antibodies, Monoclonal
  • Aged
  • Antibodies, Monoclonal
  • Female
  • Humans
  • Lymphatic Diseases (immunology, pathology)
  • Lymphoma (immunology)
  • Paget Disease, Extramammary (immunology, pathology)
  • Phenotype
  • Skin (cytology)
  • Skin Neoplasms (immunology, pathology)
  • T-Lymphocytes (classification, pathology)

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