Sickle cell anemia. Pathophysiology and treatment.

Abstract

Current concepts of the pathophysiology of the sickling process are reviewed. New approaches to treatment - including induced hyponatremia, membrane-active antisickling agents, and gene manipulation - are described.

• Authors: J B Alavi
• Journal: The Medical clinics of North America (Med Clin North Am) Vol. 68 Issue 3 Pg. 545-56 (May 1984) ISSN: 0025-7125 [Print] United States
• PMID: 6205230 (Publication Type: Journal Article, Review)

Chemical References

• Antisickling Agents
• Azepines
• Phenothiazines
• cetiedil
• Urea
• Folic Acid
• Azacitidine

Topics

• Anemia, Sickle Cell (blood, complications, therapy)
• Antisickling Agents (therapeutic use)
• Azacitidine (therapeutic use)
• Azepines (therapeutic use)
• Blood Transfusion
• Cerebrovascular Disorders (etiology)
• Child
• Child, Preschool
• Female
• Folic Acid (therapeutic use)
• Humans
• Male
• Phenothiazines (therapeutic use)
• Pneumococcal Infections (prevention & control)
• Pregnancy
• Pregnancy Complications, Hematologic (therapy)
• Priapism (etiology)
• Urea (therapeutic use)
• Vaccination