[Effect of pentamine on vascular tissue metabolism in experimental vascular pathology].

Abstract

It has been demonstrated in experiments on cats and rabbits that a single and chronic administration of pentamine (1 mg/kg) produced a distinct variation in carbohydrate-energy metabolism in the tissue of different blood vessels, enhancing the glycolytic formation of ATP. Chronic administration of pentamine corrected metabolic disorders in rabbit vascular tissue in experimental pituitrin-induced hypertension.

• Authors: A A Nikulin, A K Rachkov
• Journal: Farmakologiia i toksikologiia (Farmakol Toksikol) 1984 Jan-Feb Vol. 47 Issue 1 Pg. 57-63 ISSN: 0014-8318 [Print] Russia (Federation)
• Vernacular Title: O vliianii pentamina na metabolizm sosudistoĭ tkani pri éksperimental'noĭ sosudistoĭ patologii.
• PMID: 6200358 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Pituitary Hormones, Posterior
• Quaternary Ammonium Compounds
• pentamine

Topics

• Animals
• Blood Vessels (drug effects, metabolism, radiation effects)
• Cats
• Drug Evaluation, Preclinical
• Energy Metabolism (drug effects)
• Female
• Hypertension (chemically induced, drug therapy, metabolism)
• Male
• Pituitary Hormones, Posterior (pharmacology)
• Quaternary Ammonium Compounds (therapeutic use)
• Rabbits
• Radiation Injuries, Experimental (drug therapy, metabolism)
• Time Factors