Changes in serum proteins following implantation of pacemakers.

Abstract

The change in the protein concentration in blood serum was investigated after implantation of a pacing system with epoxide surface (group A, 20 patients) or metallic case (group B, 9 patients). The response to surgical intervention was equal in both groups. In the first period following operation the acute phase reaction took place in terms of increasing concentrations of alpha-globulins, especially alpha 1-acid glycoprotein, alpha 1-antitrypsin, ceruloplasmin, haptoglobin, and beta 1A/C-globulin, Simultaneously, a decrease in prealbumin, albumin, beta-globulin, in particular haemopexin and transferin concentration appeared. As for immunoglobulins, a decrease in IgG and increase in IgA and IgM globulins was observed. In the course of a longer period of time following implantation (group B--three months; group A--two years) a decrease of almost all investigated proteins was observed with exception of increased IgA globulin and transferin in group A.

• Authors: M Podhradská, J Vajó, J Andrasina
• Journal: Cor et vasa (Cor Vasa) Vol. 25 Issue 5 Pg. 372-80 ( 1983) ISSN: 0010-8650 [Print] Czech Republic
• PMID: 6197229 (Publication Type: Journal Article)

Chemical References

• Alpha-Globulins
• Beta-Globulins
• Blood Proteins
• Haptoglobins
• Immunoglobulins
• Orosomucoid
• Serum Albumin
• Transferrin
• alpha 1-Antitrypsin
• Hemopexin
• Ceruloplasmin

Topics

• Adult
• Aged
• Alpha-Globulins (analysis)
• Beta-Globulins (analysis)
• Blood Proteins (analysis)
• Ceruloplasmin (analysis)
• Electrophoresis, Cellulose Acetate
• Female
• Haptoglobins (analysis)
• Hemopexin (analysis)
• Humans
• Immunoelectrophoresis, Two-Dimensional
• Immunoglobulins (analysis)
• Male
• Middle Aged
• Orosomucoid (analysis)
• Pacemaker, Artificial
• Serum Albumin (analysis)
• Time Factors
• Transferrin (analysis)
• alpha 1-Antitrypsin (analysis)