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'Pink eye' or 'zere oogjes' or keratoconjunctivitis infectiosa ovis (KIO). Clinical efficacy of a number of antimicrobial therapies.

Abstract
In a comparative study the clinical efficacy of five different treatments of keratoconjunctivitis infectiosa ovis (KIO) were tested, namely an intramuscular injection of chloramphenicol base (dosage 15 mg/kg), spiramycin base (Suanovil dosages 10 to 25 mg/kg), oxytetracycline (Engemycine Forte, Terramycin LA, dosages respectively 5 and 10 mg/kg), tiamulin (Dynamutulin, dosage 10 mg/kg) and subcutaneous injection of procaine penicillin G, benzathine penicillin G. and dihydrostreptomycin in the lower eyelid. It appeared from these field trials that spiramycin base, oxytetracycline and tiamulin had a clearly positive effect on the clinical course of 'pink eye', although with tiamulin there was only a temporary effect (high percentage of relapses). In view of the field data the following dosage schemes are, for the time being, advised: spiramycin base (Suanovil), and oxytetracycline (formulation with a good biological availability) both 20 to 30 mg/kg and, if necessary, to be repeated on days 5 and 10 after the first intramuscular injection. The dosage scheme advised for tiamulin is 20-30 mg/kg to be repeated on day 3 and if necessary on days 6 and 9 after the intramuscular injection. In mild cases it is sufficient to rub the eyes with for example oxytetracycline eye-ointment, a few times a day.
AuthorsC D König
JournalThe veterinary quarterly (Vet Q) Vol. 5 Issue 3 Pg. 122-7 (Jul 1983) ISSN: 0165-2176 [Print] England
PMID6195802 (Publication Type: Comparative Study, Journal Article)
Chemical References
  • Anti-Bacterial Agents
  • Diterpenes
  • Leucomycins
  • Chloramphenicol
  • tiamulin
  • Penicillin G
  • Dihydrostreptomycin Sulfate
  • Oxytetracycline
Topics
  • Animals
  • Anti-Bacterial Agents (therapeutic use)
  • Chloramphenicol (therapeutic use)
  • Dihydrostreptomycin Sulfate (therapeutic use)
  • Diterpenes (therapeutic use)
  • Female
  • Keratoconjunctivitis (drug therapy, veterinary)
  • Leucomycins (therapeutic use)
  • Male
  • Oxytetracycline (therapeutic use)
  • Penicillin G (therapeutic use)
  • Sheep
  • Sheep Diseases (drug therapy)

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