Abstract |
In a comparative study the clinical efficacy of five different treatments of keratoconjunctivitis infectiosa ovis (KIO) were tested, namely an intramuscular injection of chloramphenicol base (dosage 15 mg/kg), spiramycin base (Suanovil dosages 10 to 25 mg/kg), oxytetracycline (Engemycine Forte, Terramycin LA, dosages respectively 5 and 10 mg/kg), tiamulin (Dynamutulin, dosage 10 mg/kg) and subcutaneous injection of procaine penicillin G, benzathine penicillin G. and dihydrostreptomycin in the lower eyelid. It appeared from these field trials that spiramycin base, oxytetracycline and tiamulin had a clearly positive effect on the clinical course of ' pink eye', although with tiamulin there was only a temporary effect (high percentage of relapses). In view of the field data the following dosage schemes are, for the time being, advised: spiramycin base (Suanovil), and oxytetracycline (formulation with a good biological availability) both 20 to 30 mg/kg and, if necessary, to be repeated on days 5 and 10 after the first intramuscular injection. The dosage scheme advised for tiamulin is 20-30 mg/kg to be repeated on day 3 and if necessary on days 6 and 9 after the intramuscular injection. In mild cases it is sufficient to rub the eyes with for example oxytetracycline eye- ointment, a few times a day.
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Authors | C D König |
Journal | The veterinary quarterly
(Vet Q)
Vol. 5
Issue 3
Pg. 122-7
(Jul 1983)
ISSN: 0165-2176 [Print] England |
PMID | 6195802
(Publication Type: Comparative Study, Journal Article)
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Chemical References |
- Anti-Bacterial Agents
- Diterpenes
- Leucomycins
- Chloramphenicol
- tiamulin
- Penicillin G
- Dihydrostreptomycin Sulfate
- Oxytetracycline
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Topics |
- Animals
- Anti-Bacterial Agents
(therapeutic use)
- Chloramphenicol
(therapeutic use)
- Dihydrostreptomycin Sulfate
(therapeutic use)
- Diterpenes
(therapeutic use)
- Female
- Keratoconjunctivitis
(drug therapy, veterinary)
- Leucomycins
(therapeutic use)
- Male
- Oxytetracycline
(therapeutic use)
- Penicillin G
(therapeutic use)
- Sheep
- Sheep Diseases
(drug therapy)
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