Immunoreactive prekeratin in Brenner tumors of the ovary.

Abstract

In an attempt to further characterize benign, proliferating, and malignant Brenner tumors, immunoperoxidase staining for prekeratin was undertaken in a group of these neoplasms as well as in a variety of histologically different tumors of the ovary. All Brenner tumors reacted positively for prekeratin, whereas none of the other epithelial or sex cord-stromal tumors of the ovary stained. On the basis of these findings, we conclude that prekeratin might be a useful marker for differentiating malignant Brenner tumors from histologically similar, poorly differentiated ovarian neoplasms.

• Authors: P Ganjei, M Nadji, N S Penneys, H E Averette, A R Morales
• Journal: International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists (Int J Gynecol Pathol) Vol. 1 Issue 4 Pg. 353-8 ( 1983) ISSN: 0277-1691 [Print] United States
• PMID: 6193073 (Publication Type: Journal Article)

Chemical References

• Protein Precursors
• prekeratin
• Keratins

Topics

• Brenner Tumor (diagnosis, metabolism)
• Female
• Histocytochemistry
• Humans
• Immunoenzyme Techniques
• Keratins (immunology, metabolism)
• Ovarian Neoplasms (diagnosis, metabolism)
• Protein Precursors (immunology, metabolism)