Failure to modify scrapie in mice by administration of interferon or anti-interferon globulin.

Abstract

Administration of potent mouse interferon preparations or anti-mouse interferon globulin did not influence the evolution of scrapie in mice after intraperitoneal injection of the agent. We conclude that the interferon system is probably not involved in scrapie.

• Authors: I Gresser, C Maury, R L Chandler
• Journal: The Journal of general virology (J Gen Virol) Vol. 64 (Pt 6) Pg. 1387-9 (Jun 1983) ISSN: 0022-1317 [Print] England
• PMID: 6189965 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Prions
• Interferons

Topics

• Animals
• Interferons (therapeutic use)
• Mice
• Prions (drug effects, pathogenicity)
• Scrapie (microbiology, therapy)
• Sheep