HOMEPRODUCTSSERVICESCOMPANYCONTACTFAQResearchDictionaryPharmaMobileSign Up FREE or Login

Rat hybridoma antibodies against canine parvovirus.

Abstract
Hybrid cells have been produced by fusion between rat myeloma cells IR983F and spleen cells from a LOU rat immunized with canine enteritis parvovirus. Four stable cell lines were selected each secreting a monoclonal antibody directed against this virus. By indirect immunofluorescence, the antigenic determinants recognized by these antibodies were found to be present not only in canine parvovirus infected cells but also in cells infected by the related parvoviruses of mink enteritis and feline panleukopenia. Two of the monoclonal antibodies inhibit hemagglutination by the canine virus and neutralize its infectivity. Hybrid cells were transplanted into histocompatible animals, and large amounts of the antibodies were obtained.
AuthorsG Burtonboy, H Bazin, N Delferriere
JournalArchives of virology (Arch Virol) Vol. 71 Issue 4 Pg. 291-302 ( 1982) ISSN: 0304-8608 [Print] AUSTRIA
PMID6178386 (Publication Type: Journal Article)
Chemical References
  • Antibodies, Monoclonal
  • Antibodies, Viral
  • Antigens, Viral
  • Epitopes
Topics
  • Animals
  • Antibodies, Monoclonal
  • Antibodies, Viral (immunology)
  • Antigen-Antibody Reactions
  • Antigens, Viral (analysis)
  • Epitopes
  • Neoplasm Transplantation
  • Parvoviridae (immunology)
  • Rats

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research network!


Choose Username:
Email:
Password:
Verify Password: