The effect of zinc-protamine-glucagon in acute pancreatitis.

Abstract

A double blind study testing the effect of long-acting zinc-protamine-glucagon (7.5 mg every 12 hours for 4--5 days) was carried out in acute pancreatitis. There were 32 patients in ZP-glucagon- and 39 patients in the placebo group. The results show that glucagon had a slightly favourable effect on the general clinical course of the disease but they do not give enough evidence for routine use of glucagon in pancreatitis.

• Authors: T V Kalima, M Lempinen
• Journal: Annales chirurgiae et gynaecologiae (Ann Chir Gynaecol) Vol. 69 Issue 6 Pg. 293-5 ( 1980) ISSN: 0355-9521 [Print] Finland
• PMID: 6163389 (Publication Type: Clinical Trial, Controlled Clinical Trial, Journal Article)

Chemical References

• Protamines
• Glucagon
• Amylases
• Zinc

Topics

• Acute Disease
• Adult
• Amylases (urine)
• Clinical Trials as Topic
• Double-Blind Method
• Female
• Glucagon (therapeutic use)
• Humans
• Male
• Middle Aged
• Pancreatitis (drug therapy)
• Protamines (therapeutic use)
• Zinc (therapeutic use)