Cyclical thrombocytopenia with remission during lynestrenol treatment in a woman.

Abstract

A woman of 40 had cyclical thrombocytopenia occurring midway between menstruations, with bruising and platelet counts down to 2000/mm3. The thrombocytopenic episodes disappeared after treatment with lynestrenol was started. The patient's platelets had a functional defect of the "aspirin-like" type. The availability of platelet factor 3 increased when oestrogen was added to platelet-rich plasma from the patient.

• Authors: P Wahlberg, D Nyman, P Ekelund, S A Carlsson, H Granlund
• Journal: Annals of clinical research (Ann Clin Res) Vol. 9 Issue 6 Pg. 356-8 (Dec 1977) ISSN: 0003-4762 [Print] Finland
• PMID: 616224 (Publication Type: Case Reports, Journal Article)

Chemical References

• Platelet Factor 3
• Norgestrel
• Ethinyl Estradiol
• Lynestrenol

Topics

• Adult
• Ethinyl Estradiol (therapeutic use)
• Female
• Humans
• Lynestrenol (therapeutic use)
• Menstruation (drug effects)
• Norgestrel (therapeutic use)
• Platelet Aggregation (drug effects)
• Platelet Factor 3 (physiology)
• Remission, Spontaneous
• Thrombocytopenia (drug therapy)