[Combination treatment of atrial arrhythmias with quinidine-verapamil].

Abstract

Between 1977 and 1979, a combined antiarrhythmic therapy with Quinidine and Verapamil was used to treat 66 patients (aged 16 to 69 years) with chronic atrial arrhythmias of different etiology. In 60% of the 43 cases with atrial fibrillation the combined therapy was effective in reversing atrial fibrillation to regular sinus rhythm. The frequency of successful responses to Quinidine - Verapamil amounted to more than twice compared with earlier therapeutic results with Quinidine only. In 65% of the 23 cases with atrial extrasystoles or atrial tachycardias a significant reduction of the ectopics could be achieved or a regular sinus rhythm could be established. Thus, the combined therapy with Quinidine - Verapamil is very effective in abolishing chronic atrial arrhythmias, especially atrial fibrillation.

• Authors: H Gülker, H U Bramann, B Brisse, H Kuhs
• Journal: Medizinische Klinik (Med Klin) Vol. 75 Issue 5 Pg. 196-8 (Feb 29 1980) ISSN: 0025-8458 [Print] Germany
• Vernacular Title: Kombinierte Behandlung chronische Vorhof-Rhythmusstörungen mit Chinidin-Verapamil.
• PMID: 6156393 (Publication Type: English Abstract, Journal Article)

Chemical References

• Anti-Arrhythmia Agents
• Verapamil
• Quinidine

Topics

• Adolescent
• Adult
• Aged
• Anti-Arrhythmia Agents (administration & dosage, therapeutic use)
• Atrial Fibrillation (drug therapy)
• Cardiac Complexes, Premature (drug therapy)
• Drug Therapy, Combination
• Female
• Heart Atria (drug effects)
• Humans
• Male
• Middle Aged
• Quinidine (administration & dosage, therapeutic use)
• Tachycardia (drug therapy)
• Verapamil (administration & dosage, therapeutic use)