Inhibition by 2',3'-dideoxythymidine of retroviral infection of mouse and human cells.

Abstract	Infection of mouse and human cells with type C murine leukemia/sarcoma viruses was inhibited by the nucleoside analogue 2',3'-dideoxythymidine (ddT). Cell growth and virus synthesis by previously infected cells were not affected by the analogue. Infection of rat cells with murine retroviruses was not inhibited by ddT.
Authors	P Furmanski, G J Bourguignon, C S Bolles, J D Corombos, M R Das
Journal	Cancer letters (Cancer Lett) Vol. 8 Issue 4 Pg. 307-15 (Feb 1980) ISSN: 0304-3835 [Print] Ireland
PMID	6154527 (Publication Type: Journal Article, Research Support, U.S. Gov't, P.H.S.)
Chemical References	Dideoxynucleosides Reverse Transcriptase Inhibitors 2',3'-dideoxythymidine Thymidine
Topics	Animals Cell Division (drug effects) Cell Transformation, Viral (drug effects) Cells, Cultured Dideoxynucleosides Humans Kirsten murine sarcoma virus (drug effects) Mice Rats Retroviridae (drug effects) Reverse Transcriptase Inhibitors Thymidine (analogs & derivatives, pharmacology)

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