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Treatment of serious obstetric and gynecologic infections with cefoxitin.

AbstractIn order to evaluate the efficacy of cefoxitin, 25 patients with serious pelvic infections admitted to a community hospital were treated with the drug. Twenty-one patients (84%) responded to this therapy. Three of the four failures (75%) had a pelvic abscess. Resistant organisms included Staphylococcus aureus, Pseudomonas aeruginosa and enterococci. The adverse reactions encountered were due to localized phlebitis, which occurred in three patients (12%). The study demonstrated that cefoxitin was successful as a single agent in the treatment of serious soft-tissue pelvic infections.
AuthorsW D Hager, P S McDaniel (Affiliation: Department of Obstetrics and Gynecology, Central Baptist Hospital, Lexington, Kentucky.)
JournalThe Journal of reproductive medicine (J Reprod Med) Vol. 28 Issue 5 Pg. 337-40 (May 1983) ISSN: 0024-7758 UNITED STATES
PMID6152988 (Publication Type: Journal Article)
Chemical References
  • Cefoxitin
Topics
  • Adult
  • Bacterial Infections (diagnosis, drug therapy, microbiology)
  • Cefoxitin (therapeutic use)
  • Drug Evaluation
  • Drug Resistance, Microbial
  • Female
  • Humans
  • Infusions, Intravenous
  • Length of Stay (statistics & numerical data)
  • Microbial Sensitivity Tests
  • Middle Aged
  • Pelvic Inflammatory Disease (diagnosis, drug therapy, microbiology)
  • Thrombophlebitis (chemically induced)
  • Treatment Failure