Effect of L-tryptophan supplementation on ischemic pain.

Abstract

The synthesis of neurotransmitter amines in mammalian brain is known to respond to changes in precursor availability. After dietary manipulation including L-tryptophan supplementation 3 subjects out of 11 showed a significant reduction of experimentally induced ischemic pain. It is suggested that dietary manipulation aimed at an increase in central nervous system serotonin can alter pain perception in some individuals.

• Authors: T Nurmikko, A Pertovaara, P J Pöntinen, K M Marnela, S S Oja
• Journal: Acupuncture & electro-therapeutics research (Acupunct Electrother Res) Vol. 9 Issue 1 Pg. 45-55 ( 1984) ISSN: 0360-1293 [Print] United States
• PMID: 6145310 (Publication Type: Journal Article)

Chemical References

• Amino Acids
• Tryptophan

Topics

• Adult
• Amino Acids (blood)
• Arm (blood supply)
• Double-Blind Method
• Female
• Humans
• Ischemia (blood, drug therapy)
• Male
• Middle Aged
• Pain (blood, drug therapy)
• Tryptophan (blood, therapeutic use)