[Therapy of acute poisoning with orthograde intestinal lavage].

Abstract

Orthograde intestinal lavage was successfully used in the treatment of eight patients with acute poisoning. Three had mushroom (Amanita pantherina) poisoning, five acute drug intoxication (attempted suicide: diazepam, dihydropyridine, crotylbarbital, phenobarbital, amitriptyline and glibenclamide). Within 5-18 hours the clinical signs of poisoning regressed in four patient in stage IV (after Reed), so that the patients became responsive. Detoxication by orthograde intestinal lavage is achieved by mechanical removal of nonabsorbed compounds from the gastro-intestinal tract and via intestinal dialysis across the intestinal mucosa.

• Authors: J Hildebrandt, G Lauschke, K D Sinkwitz, J Schmidt
• Journal: Deutsche medizinische Wochenschrift (1946) (Dtsch Med Wochenschr) Vol. 108 Issue 25 Pg. 981-4 (Jun 24 1983) ISSN: 0012-0472 [Print] Germany
• Vernacular Title: Therapie akuter Intoxikationen durch orthograde Darmspülung.
• PMID: 6133732 (Publication Type: English Abstract, Journal Article)

Chemical References

• Barbiturates
• Dihydropyridines
• Pyridines
• Amitriptyline
• 1,4-dihydropyridine
• Diazepam
• Glyburide
• crotarbital
• Phenobarbital

Topics

• Amitriptyline (poisoning)
• Barbiturates (analogs & derivatives, poisoning)
• Diazepam (poisoning)
• Dihydropyridines
• Glyburide (poisoning)
• Humans
• Intestines
• Mushroom Poisoning (therapy)
• Phenobarbital (poisoning)
• Poisoning (therapy)
• Posture
• Pyridines (poisoning)
• Suicide, Attempted
• Therapeutic Irrigation