Cerebrospinal fluid sterols in the evaluation of patients with gliomas.

Abstract

This study was an effort to obtain a marker indicative of the biologic activity of human gliomas. Sterol levels in the cerebrospinal fluid (CSF) were evaluated. Studies were conducted longitudinally during the course of tumor therapy. The evidence indicated that desmosterol levels in the CSF may reflect the growth potential of these neoplasms.

• Authors: J Ransohoff, J Weiss
• Journal: National Cancer Institute monograph (Natl Cancer Inst Monogr) Vol. 46 Pg. 119-24 (Dec 1977) ISSN: 0083-1921 [Print] United States
• PMID: 613222 (Publication Type: Journal Article)

Chemical References

• Desmosterol
• Triparanol
• Cholesterol

Topics

• Adult
• Aged
• Brain Neoplasms (cerebrospinal fluid, diagnosis, therapy)
• Cholesterol (cerebrospinal fluid)
• Desmosterol (cerebrospinal fluid)
• Glioma (cerebrospinal fluid, diagnosis, therapy)
• Humans
• Male
• Middle Aged
• Triparanol