[Favorable course of severe talinolol poisoning].

Abstract

It is reported on a severe talinolol intoxication of a 19-year-old female patient who on suicidal purpose had taken 1.25-1.5 g talinolol (cordanum) (= 25-30 mg/kg body weight). Symptoms were non-measurable blood pressure and pulse, broadening of QRS with bradycardic disturbance of the rhythm in the ECG as well as severe abdominal pain, however, no bronchospasm. After unsuccessful application of orciprenalin and dopamin intracardiac transvenous electrostimulation with following improvement of the circulatory stimulation and the general condition. The highly frequent atrial stimulation performed before the discharge on the 6th day of the stay in hospital resulted in references to a disturbance of the sinu-auricular node automatism.

• Authors: A Weihermüller, U Bloch
• Journal: Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete (Z Gesamte Inn Med) Vol. 37 Issue 16 Pg. 542-3 (Aug 15 1982) ISSN: 0044-2542 [Print] Germany
• Vernacular Title: Günstiger Verlauf einer schweren Talinololintoxikntion.
• PMID: 6128836 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Adrenergic beta-Antagonists
• Propanolamines
• talinolol
• Dopamine

Topics

• Adrenergic beta-Antagonists (poisoning)
• Adult
• Arrhythmias, Cardiac (chemically induced)
• Cardiac Pacing, Artificial
• Dopamine (therapeutic use)
• Electrocardiography
• Female
• Hemodynamics (drug effects)
• Humans
• Prognosis
• Propanolamines (poisoning)
• Suicide, Attempted