Increased non-protein-bound iron and decreased protection against superoxide-radical damage in cerebrospinal fluid from patients with neuronal ceroid lipofuscinoses.

• Authors: J M Gutteridge, D A Rowley, B Halliwell, T Westermarck
• Journal: Lancet (London, England) (Lancet) Vol. 2 Issue 8296 Pg. 459-60 (Aug 28 1982) ISSN: 0140-6736 [Print] England
• PMID: 6125637 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Ceroid
• Free Radicals
• Lipofuscin
• Pigments, Biological
• Superoxides
• Iron

Topics

• Adolescent
• Age Factors
• Central Nervous System Diseases (cerebrospinal fluid)
• Ceroid (metabolism)
• Child
• Child, Preschool
• Free Radicals
• Humans
• Infant
• Iron (cerebrospinal fluid)
• Lipofuscin (metabolism)
• Neurons
• Oxidation-Reduction
• Pigments, Biological (metabolism)
• Protein Binding
• Sphingolipidoses (cerebrospinal fluid)
• Superoxides (cerebrospinal fluid)