Propoxyphene napsylate maintenance treatment for narcotic dependence: a non-methadone model.

One hundred and seventy eight heroin addicts entered propoxyphene napsylate (PN) maintenance. Patients attended a general medical clinic twice each week and took home a three- to four-day supply of PN, to be taken in doses of 300 to 400 mg three or four times per day. Over a 21-month period, subjects entered and re-entered PN treatment 266 times (1.5 times per patient) and remained in treatment a mean of 10.6 weeks. When compared with a group of methadone maintenance patients, similar characteristics in employment and heroin use were found. The ability to take PN, attend a clinic less often than daily and discontinue and re-enter treatment on a discretionary basis is a preferred treatment approach for some narcotic addicts.
AuthorsF S Tennant Jr, R A Rawson
JournalDrug and alcohol dependence (Drug Alcohol Depend) Vol. 8 Issue 1 Pg. 79-83 (Aug 1981) ISSN: 0376-8716 [Print] SWITZERLAND
PMID6117456 (Publication Type: Journal Article)
Chemical References
  • Morphine
  • Dextropropoxyphene
  • Adult
  • Alcohol Drinking
  • Dextropropoxyphene (analogs & derivatives, therapeutic use)
  • Female
  • Heroin Dependence (psychology, rehabilitation)
  • Humans
  • Male
  • Middle Aged
  • Morphine (urine)
  • Social Adjustment

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