HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

[Effect of different FiO2 on the ventilatory action of almitrine in the anesthetized dog. Preliminary study].

Abstract
The effects of progressively increasing hyperoxia from 0.22 to 1 on the ventilatory action of a ventilatory analeptic with a peripheral action, almitrine, were studied in six dogs under deep anaesthesia by Alfatesine administered at a constant flow rate. At FiO2 = o.22, almitrine partially corrected hypoventilation. From FiO2 o.30 to FiO2 0.50, initial hypoventilation was unaltered. At FiO2 = 1, it was worsened. This preliminary study will need to be completed by examination of the interference almitrine-FiO2 at different levels of anaesthesia and of respiratory depression, by study of the effects of different levels of FiO2 on the respiratory depression caused by Alfatesine and by study of the effects of the sudden administration of pure oxygen.
AuthorsJ H Gaudy, C Dauthier, F Férracci, J F Boitier
JournalAnnales de l'anesthesiologie francaise (Ann Anesthesiol Fr) Vol. 21 Issue 2 Pg. 145-7 ( 1980) ISSN: 0003-4061 [Print] France
Vernacular TitleEffet de différents niveaux de FiO2 sur l'action ventilatoire de l'almitrine chez le chien anesthésié. Etude préliminaire.
PMID6109490 (Publication Type: English Abstract, Journal Article)
Chemical References
  • Piperazines
  • Triazines
  • Almitrine
  • Oxygen
Topics
  • Almitrine
  • Anesthesia
  • Animals
  • Dogs
  • Oxygen (pharmacology)
  • Piperazines (pharmacology)
  • Respiration, Artificial
  • Triazines (pharmacology)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: