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Azatadine maleate/pseudoephedrine sulfate repetabs versus placebo in the treatment of severe perennial allergic rhinitis.

Abstract
Sixty patients took part in a randomized double-blind comparison of azatadine/pseudoephedrine versus placebo for the treatment of severe perennial allergic rhinitis. After 2 weeks of therapy subjective patient appraisal as well as objective physician evaluation showed the active drug combination to have a beneficial effect (72% good to excellent improvement versus 40% for placebo) in reducing the signs and symptoms of this allergic disorder. No adverse reactions were reported.
AuthorsJ Zubizaretta
JournalThe Journal of international medical research (J Int Med Res) Vol. 8 Issue 6 Pg. 395-9 ( 1980) ISSN: 0300-0605 [Print] England
PMID6108263 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)
Chemical References
  • Delayed-Action Preparations
  • Drug Combinations
  • Histamine H1 Antagonists
  • Cyproheptadine
  • azatadine
  • Ephedrine
Topics
  • Adolescent
  • Adult
  • Aged
  • Cyproheptadine (analogs & derivatives, therapeutic use)
  • Delayed-Action Preparations
  • Double-Blind Method
  • Drug Combinations
  • Ephedrine (therapeutic use)
  • Female
  • Histamine H1 Antagonists (therapeutic use)
  • Humans
  • Male
  • Middle Aged
  • Rhinitis, Allergic, Seasonal (drug therapy)

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