Abstract |
Sixty patients took part in a randomized double-blind comparison of azatadine/ pseudoephedrine versus placebo for the treatment of severe perennial allergic rhinitis. After 2 weeks of therapy subjective patient appraisal as well as objective physician evaluation showed the active drug combination to have a beneficial effect (72% good to excellent improvement versus 40% for placebo) in reducing the signs and symptoms of this allergic disorder. No adverse reactions were reported.
|
Authors | J Zubizaretta |
Journal | The Journal of international medical research
(J Int Med Res)
Vol. 8
Issue 6
Pg. 395-9
( 1980)
ISSN: 0300-0605 [Print] England |
PMID | 6108263
(Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)
|
Chemical References |
- Delayed-Action Preparations
- Drug Combinations
- Histamine H1 Antagonists
- Cyproheptadine
- azatadine
- Ephedrine
|
Topics |
- Adolescent
- Adult
- Aged
- Cyproheptadine
(analogs & derivatives, therapeutic use)
- Delayed-Action Preparations
- Double-Blind Method
- Drug Combinations
- Ephedrine
(therapeutic use)
- Female
- Histamine H1 Antagonists
(therapeutic use)
- Humans
- Male
- Middle Aged
- Rhinitis, Allergic, Seasonal
(drug therapy)
|