A case of 17alpha-hydroxylase deficiency with symptoms mimicking testicular feminization.

Abstract

A case of 17alpha-hydroxylase deficiency mimicking testicular feminization is reported. Different from the complete form of testicular feminization in which androgens are normal or elevated and end-organ insensitivity to androgens is supposed, this case had a negligible amount of androgens and responded to the injection of testosterone propionate with a positive nitrogen and phosphate balance.

• Authors: T Saruta, H Tachibana, K Kondo, I Saito, Y Takabayashi, S Tamura, S Fukuchi, S Matsuki
• Journal: The American journal of the medical sciences (Am J Med Sci) 1977 Nov-Dec Vol. 274 Issue 3 Pg. 333-8 ISSN: 0002-9629 [Print] United States
• PMID: 610421 (Publication Type: Case Reports, Journal Article)

Chemical References

• Hormones
• Testosterone
• Mixed Function Oxygenases

Topics

• Adult
• Androgen-Insensitivity Syndrome (diagnosis, drug therapy, enzymology)
• Diagnosis, Differential
• Female
• Hormones (metabolism)
• Humans
• Mixed Function Oxygenases (deficiency)
• Testosterone (therapeutic use)