Etomidate in electroconvulsive therapy. A within-patient comparison with alphaxalone/alphadalone.

Abstract

In a group of 31 patients undergoing electroconvulsive therapy, there was no significant difference between the times of return of eyelash reflex, swallowing and respiration following a single induction dose of 0.2 mg/kg of etomidate as compared with an induction dose of 0.036 ml/kg of alphaxalone/alphadalone. The incidence of involuntary movements and increased muscle tone was significantly greater after etomidate than following alphaxalone/alphadalone; but the involuntary movements were never marked. The overall incidence of pain on injection was 15% after etomidate. There was a low incidence of venous sequelae following either drug.

• Authors: T M O'Carroll, C E Blogg, E A Hoinville, T M Savege
• Journal: Anaesthesia (Anaesthesia) Vol. 32 Issue 9 Pg. 868-72 (Oct 1977) ISSN: 0003-2409 [Print] England
• PMID: 603002 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)

Chemical References

• Imidazoles
• Pregnanediones
• Alfaxalone Alfadolone Mixture
• Etomidate

Topics

• Adolescent
• Adult
• Aged
• Alfaxalone Alfadolone Mixture (adverse effects)
• Anesthesia, Intravenous (adverse effects)
• Electroconvulsive Therapy
• Etomidate (adverse effects)
• Female
• Humans
• Imidazoles (adverse effects)
• Male
• Middle Aged
• Pregnanediones (adverse effects)