SearchDictionaryMobileLogin

HLA in primary atrophic hypothyroidism and Hashimoto goitre.

AbstractThe prevalence of HLA-B8 was found to be significantly increased in patients with primary atrophic (no goitre) hypothyroidism, but not in goitrous patients with Hashimoto thyroiditis, whether euthroid or hypothroid. There was no correlation between the occurrence of HLA-B8 and the presence of titres of thyroid antibodies at diagnosis or their persistence for at least three years after diagnosis.
AuthorsW J Irvine, R S Gray, P J Morris, A Ting
JournalJournal of clinical & laboratory immunology (J Clin Lab Immunol) Vol. 1 Issue 3 Pg. 193-5 (Nov 1978) ISSN: 0141-2760 ITALY
PMID583053 (Publication Type: Journal Article)
Chemical References
  • Autoantibodies
  • HLA Antigens
  • Thyroglobulin
Topics
  • Adult
  • Aged
  • Autoantibodies
  • Autoimmune Diseases (immunology)
  • Female
  • HLA Antigens
  • Humans
  • Hypothyroidism (immunology)
  • Male
  • Microsomes (immunology)
  • Middle Aged
  • Thyroglobulin (immunology)
  • Thyroid Gland (immunology)
  • Thyroiditis, Autoimmune (immunology)