Serum glycylproline p-nitroanilidase activity in blood cancers.

Abstract

Glycylproline p-nitroanilidase activity in serum of patients with acute lymphatic leukemia, lymphosarcoma and Hodgkin's disease, and of normal neonates (umbilical blood) was significantly lower than that of normal adult controls. In contrast, the enzyme activity of patients with myelocytic leukemias did not differ significantly from that of normal controls.

• Authors: K Fujita, M Hirano, K Tokunaga, I Nagatsu, T Nagatsu, S Sakakibara
• Journal: Clinica chimica acta; international journal of clinical chemistry (Clin Chim Acta) Vol. 81 Issue 2 Pg. 215-7 (Dec 01 1977) ISSN: 0009-8981 [Print] Netherlands
• PMID: 579337 (Publication Type: Journal Article)

Chemical References

• Dipeptides
• Endopeptidases
• Dipeptidyl-Peptidases and Tripeptidyl-Peptidases
• glycylproline 4-nitroanilidase

Topics

• Dipeptides
• Dipeptidyl-Peptidases and Tripeptidyl-Peptidases
• Endopeptidases (blood)
• Fetal Blood (enzymology)
• Hodgkin Disease (enzymology)
• Humans
• Leukemia (enzymology)
• Lymphoma, Non-Hodgkin (enzymology)
• Methods