[Obstetrical problems in patients with Glanzmann's thrombasthenia. A casuistic presentation (author's transl)].

Abstract

Glanzmann's thrombasthenia is a rare, autosomal recessive disorder of bleeding arrest. The differential diagnosis of this platelet defect with respect to recently gained knowledge is presented in the case of a pregnant woman. Because of pelvic presentation a cesarean section was performed after adequate platelet substitution, which did not involve excessive blood loss. A severe puerperal infection necessitated an abdominal hysterectomy after appropriate platelet transfusion. The difficulties in testing platelet function in the newborn are discussed. The effectiveness of a commercially available homologous phospholipide complex (Fibraccel) was tested on the patient in a noncritical phase. The results appear important for general procedure when pregnancy and platelet dysfunction concur.

• Authors: H Heyes, R Scheck, H Rasche
• Journal: Geburtshilfe und Frauenheilkunde (Geburtshilfe Frauenheilkd) Vol. 39 Issue 1 Pg. 68-74 (Jan 1979) ISSN: 0016-5751 [Print] Germany
• Vernacular Title: Geburtshilfliche Probleme bei Thrombasthenie Glanzmann-Naegeli.
• PMID: 570532 (Publication Type: Case Reports, English Abstract, Journal Article)

Topics

• Adult
• Breech Presentation
• Cesarean Section
• Female
• Humans
• Hysterectomy
• Infant, Newborn
• Pregnancy
• Pregnancy Complications, Hematologic (therapy)
• Puerperal Infection (surgery)
• Purpura, Thrombocytopenic (genetics, therapy)
• Syndrome