Hippocampal correlates of aversive mibdrain stimulation.

Abstract

Hippocampal synchronization during aversive dorsal midbrain stimulation was observed in rats both in a conditioning procedure and under d-tubo-curarine paralysis. The results restrict the generality of previous reports which correlated hippocampal synchronization and desynchronization with approach and withdrawal behavior, respectively. Relative to the condition of free movement, curarization reduced the frequency of both "spontaneous" and dorsal midbrain-evoked synchronization, thus suggesting possible direct and indirect effects of d-tubocurarine on subcortical structures.

• Authors: A Routtenberg, R C Kramis
• Journal: Science (New York, N.Y.) (Science) Vol. 160 Issue 3834 Pg. 1363-5 (Jun 21 1968) ISSN: 0036-8075 [Print] United States
• PMID: 5656021 (Publication Type: Journal Article)

Chemical References

• Tubocurarine

Topics

• Animals
• Behavior, Animal
• Conditioning, Psychological
• Electric Stimulation
• Escape Reaction
• Hippocampus (physiology)
• Mesencephalon (physiology)
• Motivation
• Paralysis (chemically induced)
• Psychophysiology
• Rats
• Reward
• Tubocurarine (pharmacology)